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That is a principled method to make use of the paired-conclusion data, because it demonstrates greater the character from the paired-stop reads, namely, The point that the mates are pieces (ends) of precisely the same sequence. This solution improves the sensitivity from the algorithm, as just one appropriate anchor from one of many mates is ample to properly align the complete browse.

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Different accuracy metrics for splice junction detection inside the experimental RNA-seq knowledge. The colour-coding scheme for mappers is the same in all plots. X

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ranging from the initial foundation of the examine. As the go through in this instance comprises a splice junction, it cannot be mapped contiguously on the genome, and so the very first seed might be mapped to a donor splice internet site. Future, the MMP

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Different accuracy metrics for splice junction detection within the experimental RNA-seq facts. The color-coding plan for mappers is the same in all plots. X

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